3-fluoro-4-(hydroxyMethyl)phenylboronic acid

3-fluoro-4-(hydroxyMethyl)phenylboronic acid - Names and Identifiers

Name	3-fluoro-4-(hydroxyMethyl)phenylboronic acid
Synonyms	3-floro-4-hydroxymethylbenzeneboronicacid 3-Fluoro-4-hydroxymethylbenzeneboronic acid 3-fluoro-4-(hydroxyMethyl)phenylboronic acid (3-Fluoro-4-(hydroxymethyl)phenyl)boronicacid (3-Fluoro-4-(hydroxymethyl)phenyl)boronic acid Boronic acid, B-[3-fluoro-4-(hydroxymethyl)phenyl]-
CAS	1082066-52-1

3-fluoro-4-(hydroxyMethyl)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C7H8BFO3
Molar Mass	169.95
Density	1.35±0.1 g/cm3(Predicted)
Boling Point	360.9±52.0 °C(Predicted)
pKa	7.45±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-fluoro-4-(hydroxyMethyl)phenylboronic acid - Introduction

3-fluoro-4-hydroxymethylphenylboronic acid is an organic compound with the chemical formula C7H6BFO3.

Its nature is solid and can be dissolved in water. It is a weak acid that releases a hydrogen ion in aqueous solution. The compound has good stability and high stability to heat and light.

3-Fluoro-4-hydroxymethylphenylboronic acid has a wide range of applications in chemical research and synthesis. Among them, it is often used as an acid catalyst in organic synthesis, and can participate in esterification reactions, condensation reactions and other reaction processes. It is also commonly used in the introduction and removal of protecting groups in organic synthesis.

There are various methods for preparing 3-fluoro-4-hydroxymethylphenylboronic acid. A common method is to react p-fluoroanisole with triphenylboron under basic conditions, followed by heating and hydrolysis to obtain the product.

Last Update：2024-04-10 22:29:15